Pharmacological indices in antibiotic therapy
نویسندگان
چکیده
منابع مشابه
Pharmacological indices in antibiotic therapy.
After 60 years of antibiotic treatment, attempts to rationalize it have culminated in the use of pharmacological indices. These indices facilitate comparison of the activity of different antibiotics and serve as a sound basis for antibiotic dosing. Pharmacokinetic parameters (e.g. AUC, Cmax) and pharmacodynamic parameters (mostly MIC) are used for this purpose. For the so-called concentration-d...
متن کاملPharmacological Therapy in Fibromyalgia
The management of fibromyalgia patients involves a complex interplay between pharmacological management of pain and associated symptoms and the use of non-pharmacological modalities. As the elimination of all FMS symptoms (i.e. a cure) is not currently possible; the philosophy of management is symptom palliation and functional restoration. The presentation of fibromyalgia symptomatology is high...
متن کاملHow to measure the impacts of antibiotic resistance and antibiotic development on empiric therapy: new composite indices
OBJECTIVES We aimed to construct widely useable summary measures of the net impact of antibiotic resistance on empiric therapy. Summary measures are needed to communicate the importance of resistance, plan and evaluate interventions, and direct policy and investment. DESIGN, SETTING AND PARTICIPANTS As an example, we retrospectively summarised the 2011 cumulative antibiogram from a Toronto ac...
متن کاملsystemic antibiotic therapy in periodontics
systemic antibiotics in conjunction with scaling and root planing (srp), can offer an additional benefi t over srp alone in the treatment of periodontitis, in terms of clinical attachment loss (cal) and pocket depth change, and reduced risk of additional cal loss. however, antibiotics are not innocuous drugs. their use should be justifi ed on the basis of a clearly established need and should n...
متن کاملAntibiotic Guidelines : Pharmacological Parameters to be Considered
The aim of antibiotic guidelines is to provide guidance on the rational use of antibiotics, so that they serve effectively and eficiently with the least adverse effects on patients and co,n,tturtity. Tlrc iupact of such strategy nny also be seen in the containtnent of cost without ieopardizing the patient to un-successful atteupts of antibiotic treatnent. Guidelines have to satisfy certain requ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2003
ISSN: 1460-2091
DOI: 10.1093/jac/dkg482